Grants.gov is a Web site developed by the federal government to be the single portal for submitting all proposals to the 26 federal grant-making agencies. Grants.gov lists all federal grant opportunities and provides a mechanism to apply for those opportunities. Federal sponsors have begun to require proposals to be submitted electronically through Grants.gov; these proposals are then forwarded to the respective agencies. Grants.gov staff have been working with the federal agencies to create a new common set of forms, known as the SF 424 and SF 424 R&R, for proposals to be used by all agencies.

The University of Minnesota will use EGMS to transmit proposals “system-to-system” to Grants.gov.

The EGMS team is now working to enable submission of proposals through EGMS directly to Grants.gov. This functionality is called "System-to-System" (S2S) and it will be available to EGMS users as soon as testing is completed.

• EGMS performs complex budget calculations for the user. PureEdge can only hold data and cannot handle multiple fringe benefit or indirect cost calculations.
• EGMS proposals can be cloned for use multiple times. PureEdge forms cannot be reused.
• EGMS supports multiple people working on a proposal at the same time. PureEdge is only available for entry of data by one person at a time.
• EGMS can be used to create individual PDF attachments to be uploaded into PureEdge.
• EGMS can be used to create PDF versions of 424 R&R forms (populated with user-entered data) to use as guides while working in PureEdge.
• EGMS is an online system, allowing users to create their proposals online and then be able to access them via the Internet at any time from anywhere. PureEdge forms sit on a single user’s desktop and cannot be accessed via the Internet.
• EGMS-generated PDFs can be used for cutting and pasting data into PureEdge form fields.